All major cannabinoids compared
| Cannabinoid | Psychoactive? | Source | Federally legal? | Drug test risk | Smokeless formats | We feature? |
|---|---|---|---|---|---|---|
| CBD | No | Hemp (natural) | ✓ Yes | Low (isolate/broad) | Edibles, tinctures, capsules, topicals | ✓ All formats |
| Delta-9 THC | Yes | Hemp (natural, ≤0.3%) | ✓ Hemp edibles only | High | Edibles, tinctures (hemp-derived) | ✓ Hemp edibles only |
| Delta-8 THC | Mildly | CBD-converted (semi-synthetic) | ⚠ Gray area | High (same as D9) | Edibles, tinctures available | ✗ Not currently |
| HHC | Yes | Hydrogenated THC (synthetic process) | ⚠ Unclear | Unknown / likely high | Edibles available | ✗ Not currently |
| CBN | No | Hemp (natural, minor) | ✓ Yes | Low | Edibles, tinctures, capsules | ✓ In combo products |
| CBG | No | Hemp (natural, minor) | ✓ Yes | Low | Edibles, tinctures, capsules | ✓ In combo products |
CBD — Cannabidiol
The most abundant non-psychoactive cannabinoid in hemp. Won't get you high at any dose. Interacts with the endocannabinoid system through a different mechanism than THC. The foundation of everything we cover at CBDBrands.Shop.
What it is and how it works
CBD is a phytocannabinoid — a cannabinoid produced by a plant rather than your body. It interacts with CB1 and CB2 receptors in your endocannabinoid system, but indirectly and weakly compared to THC. It also affects serotonin receptors, TRPV1 channels, and other non-ECS targets.
This multi-target interaction is why CBD's effects are broad and why research across different conditions shows promise. It is also why effects can feel subtle — CBD works with the body's regulatory systems rather than overriding them the way THC does.
Extract types matter
Full spectrum CBD (with trace THC) produces stronger effects through the entourage effect. Broad spectrum removes THC. Isolate is pure CBD only. The type you choose affects both effectiveness and drug test risk.
What research suggests
- The FDA has approved one CBD drug (Epidiolex) for specific seizure disorders
- Research suggests potential for anxiety, sleep, inflammation, and pain
- Most clinical research uses much higher doses than consumer products contain
- Not a substitute for professional medical treatment
Smokeless formats available
- Edibles — gummies, chocolates, mints
- Tinctures and oils — sublingual
- Capsules and softgels
- Topicals — creams, balms, roll-ons
Delta-9 THC
The original THC. The compound most people think of when they hear "cannabis." Psychoactive — will produce a high. Legal as hemp-derived edibles under 0.3% by dry weight under the 2018 Farm Bill. A growing and legitimate product category for smokeless wellness.
Why hemp-derived Delta-9 edibles are legal
The 2018 Farm Bill legalized hemp-derived compounds including Delta-9 THC as long as the hemp plant contains less than 0.3% Delta-9 by dry weight. Because edibles weigh several grams each, a single piece can legally contain 10–15mg of real Delta-9 THC and still be within the 0.3% threshold by dry weight.
This means hemp-derived Delta-9 edibles contain real, psychoactive THC — the same compound found in marijuana — just at a dose size that happens to comply with Farm Bill math. Legal does not mean non-intoxicating.
Starting dose guidance
2.5–5mg for first-timers. 10–15mg is a moderate dose. Hemp-derived Delta-9 edibles can be just as potent as dispensary products at equivalent doses. Do not drive. Do not combine with alcohol.
Effects at typical edible doses
- Euphoria and mood elevation
- Body relaxation
- Altered time perception
- Increased appetite
- Possible anxiety at high doses in sensitive individuals
Important considerations
- Will fail standard THC drug tests
- Not appropriate for those under 21
- Do not use if pregnant or breastfeeding
- Impairs driving — treat like alcohol in that context
- COA must confirm Farm Bill compliance (<0.3% by dry weight)
Delta-8 THC
A naturally occurring cannabinoid in hemp, but found in such tiny amounts that commercial products are made by chemically converting CBD into Delta-8. Produces milder psychoactive effects than Delta-9. Exists in a significant legal gray area — banned in 14+ states. We do not currently feature Delta-8 products.
What it actually is
Delta-8 THC occurs naturally in hemp but at concentrations below 0.1% — far too little to extract economically. The Delta-8 in virtually all commercial products is produced by treating CBD with acidic catalysts in a process called isomerization. This makes Delta-8 a semi-synthetic cannabinoid, derived from natural CBD through a chemical process.
The FDA has issued warnings about Delta-8 products, noting adverse event reports including hallucinations, vomiting, anxiety, and loss of consciousness — in some cases associated with contaminated products from unregulated manufacturing.
How it compares to Delta-9
- Generally 50–70% as potent as Delta-9 at equivalent doses
- Users report less anxiety and clearer effects
- Will fail drug tests the same as Delta-9
- Drug test claim that "it won't show" is unsubstantiated
- Duration similar — 4–8 hours for edibles
Why we don't feature it
Legal status is actively contested and varies by state. Quality inconsistency in the market is significant. FDA warnings exist. The risk profile does not meet our standard for recommending products to first-time buyers.
HHC — Hexahydrocannabinol
The newest major cannabinoid to enter the consumer market. Produced by hydrogenating THC — a chemical process similar to turning vegetable oil into margarine. Psychoactive effects reported as similar to Delta-9. Very limited safety research exists. Legal status is actively evolving. We do not currently feature HHC products.
How HHC is made
HHC is produced by adding hydrogen atoms to THC molecules under pressure with a catalyst — a process called hydrogenation. It exists naturally in cannabis seeds and pollen in trace amounts, but commercial HHC is entirely manufactured. This makes it the most chemically processed of the major cannabinoids currently on the market.
The hydrogenation process produces two variants: 9R-HHC (psychoactive) and 9S-HHC (less active). The ratio in commercial products is not standardized or consistently disclosed, making dosing guidance essentially guesswork.
What we know — and don't know
- Reported effects similar to Delta-9 — euphoria, relaxation, altered perception
- No peer-reviewed safety studies specific to HHC in humans
- Claims it "won't show on drug tests" are not reliably substantiated
- Legal status contested — not clearly covered by Farm Bill protections
- Production quality highly variable across market
Our position
We will not feature HHC products until the legal landscape clarifies and sufficient safety research exists. This is consistent with our editorial standard — we only recommend products we can verify meet quality and safety criteria.
CBN, CBG, CBC and beyond
Beyond CBD and THC, hemp contains dozens of minor cannabinoids present in smaller concentrations. Several are increasingly appearing in consumer products — often combined with CBD for targeted effects.
Forms naturally as THC degrades over time. Often marketed for sleep — some preliminary research supports mild sedative properties. Non-psychoactive at typical doses. Commonly found in CBD+CBN sleep products.
Non-psychoactive · Sleep focusCalled the "mother cannabinoid" — both CBD and THC derive from CBGA. Non-psychoactive. Preliminary research suggests anti-inflammatory and neuroprotective properties. Marketed for focus and daytime use.
Non-psychoactive · Focus/daytimeThird most abundant cannabinoid in hemp after CBD and THC. Non-psychoactive. Research is early-stage. Believed to contribute to the entourage effect. Rarely appears as a standalone ingredient — more common in full spectrum products.
Non-psychoactive · Entourage effectThe acidic precursor to CBD found in raw hemp. Not produced in significant quantities through standard extraction. Some research suggests potential anti-nausea properties. Niche — appears in specialized raw hemp products.
Non-psychoactive · Emerging researchA structural analog of THC. Psychoactive at high doses but may actually suppress appetite at lower doses — opposite to THC. Sometimes marketed as "diet weed." Very limited human research. Rare in hemp-derived products.
Mildly psychoactive · Limited researchAromatic compounds that give hemp its smell and flavor. Found in full spectrum and broad spectrum products. Believed to contribute to the entourage effect alongside cannabinoids. Examples: myrcene (relaxing), limonene (uplifting), linalool (calming).
Non-psychoactive · Entourage effectReady to shop verified smokeless products?
We feature CBD and hemp-derived Delta-9 edibles — independently verified, COA-checked, smokeless only. No Delta-8, no HHC, no smoke.